Calponin-1肌動(dòng)蛋白結(jié)合蛋白（兔單克隆抗體）

廣州健侖生物科技有限公司

鈣調(diào)蛋白是細(xì)胞第二信使系統(tǒng)的重要成分，在Ca信號(hào)系統(tǒng)傳導(dǎo)中起著關(guān)鍵的作用，調(diào)控生理代謝及基因表達(dá)，控制細(xì)胞正常的生長(zhǎng)和發(fā)育。鈣調(diào)蛋白作為第二信使在植物信號(hào)轉(zhuǎn)導(dǎo)中的作用一直是植物生理、細(xì)胞生物學(xué)和發(fā)育生物學(xué)研究的熱點(diǎn)。Ca/CaM是有機(jī)體進(jìn)化過(guò)程中zui保守的信號(hào)轉(zhuǎn)導(dǎo)級(jí)聯(lián)反應(yīng)系統(tǒng)，這一信號(hào)途徑廣泛存在于真核細(xì)胞中，并在各種細(xì)胞活動(dòng)如脅迫反應(yīng)和細(xì)胞增殖中起調(diào)節(jié)作用。這種Ca/CaM信號(hào)系統(tǒng)存在的普遍性和保守性·對(duì)鈣調(diào)蛋白的研究可以使我們可以更好地利用其功能為人類服務(wù)。

我司還提供其它進(jìn)口或國(guó)產(chǎn)試劑盒：登革熱、瘧疾、流感、A鏈球菌、合胞病毒、腮病毒、乙腦、寨卡、黃熱病、基孔肯雅熱、克錐蟲病、違禁品濫用、肺炎球菌、軍團(tuán)菌、化妝品檢測(cè)、食品安全檢測(cè)等試劑盒以及日本生研細(xì)菌分型診斷血清、德國(guó)SiFin診斷血清、丹麥SSI診斷血清等產(chǎn)品。

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【產(chǎn)品介紹】

細(xì)胞定位：細(xì)胞漿

克隆號(hào)：EP798Y

同型：IgG

適用組織：石蠟/冰凍

陽(yáng)性對(duì)照：闌尾

抗原修復(fù)：熱修復(fù)（EDTA）

抗體孵育時(shí)間：30-60min

Calponin-1肌動(dòng)蛋白結(jié)合蛋白（兔單克隆抗體）

5、出院標(biāo)準(zhǔn)
臨床癥狀與體征消失，精神、食欲恢復(fù)，血、腦脊液等常規(guī)檢查正常，培養(yǎng)陰性。
安全提示編輯
1、在疑有曲菌感染的環(huán)境工作時(shí)，應(yīng)作好防護(hù)工作，如戴防護(hù)口罩以免吸入大量病菌。在真菌實(shí)驗(yàn)室進(jìn)行煙曲菌、黃曲菌、黑曲菌等菌的操作時(shí)，更要注意防止將這些病菌吸入肺部。[2] 
2、加強(qiáng)防護(hù)措施，如在粉塵多的地方工作時(shí)需戴上口罩，及時(shí)處理眼和皮膚的外傷，盡量消除或減少各種誘發(fā)因素的影響，積極治療慢性病。
百日咳桿菌為卵圓形短小桿菌，大小為0.5～1.5×0.2～0.5um，屬鮑特氏菌屬Bordela)，無(wú)鞭毛、芽胞。革蘭氏染色陰性。用甲苯胺藍(lán)染色可見兩極異染顆粒。專性需氧，初次分離培養(yǎng)時(shí)營(yíng)養(yǎng)要求較高，需用馬鈴薯血液甘油瓊脂培養(yǎng)基（即鮑～金氏培養(yǎng)基）才能生長(zhǎng)。經(jīng)37℃2～3天培養(yǎng)后，可見細(xì)小、圓形、光滑、凸起、銀灰色、不透明的菌落，周圍有模糊的溶血環(huán)。液體培養(yǎng)呈均勻混濁生長(zhǎng)，并有少量粘性沉淀。
生物學(xué)性狀
生化反應(yīng)弱，一般不發(fā)酵糖類，但分解蔗糖和乳糖，產(chǎn)酸不產(chǎn)氣，不產(chǎn)生H2S和吲哚，過(guò)氧化氫酶試驗(yàn)陽(yáng)性。
本菌常發(fā)生光滑型到粗糙的相變異：Ⅰ相為光滑型，菌落光滑，有莢膜，毒力強(qiáng)；Ⅳ相為粗糙型，菌落粗糙，無(wú)莢膜，無(wú)毒力。Ⅱ、Ⅲ相為過(guò)渡相。一般在疾病急性期分離的細(xì)菌為Ⅰ相，疾病晚期和多次傳代培養(yǎng)可出現(xiàn)Ⅱ、Ⅲ或Ⅳ相的變異。發(fā)生這種變異時(shí)，細(xì)菌形態(tài)、菌落、溶血性、抗原結(jié)構(gòu)和致病力等均出現(xiàn)變異。
百日咳桿菌含有耐熱的菌體（O）抗原和不耐熱的莢膜（K）抗原。前者為鮑特氏菌屬共同抗原，后者僅存于百日咳桿菌。
本菌抵抗力弱。56℃30分鐘、日光照射1小時(shí)可致死亡。對(duì)多粘菌素、氯霉素、紅霉素、氨芐青霉素等敏感，對(duì)青霉素不敏感。

Calponin-1

我司還提供其它進(jìn)口或國(guó)產(chǎn)試劑盒：登革熱、瘧疾、流感、A鏈球菌、合胞病毒、腮病毒、乙腦、寨卡、黃熱病、基孔肯雅熱、克錐蟲病、違禁品濫用、肺炎球菌、軍團(tuán)菌、化妝品檢測(cè)、食品安全檢測(cè)等試劑盒以及日本生研細(xì)菌分型診斷血清、德國(guó)SiFin診斷血清、丹麥SSI診斷血清等產(chǎn)品。

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【公司名稱】 廣州健侖生物科技有限公司
【市場(chǎng)部】    楊永漢

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【騰訊  】 
【公司地址】 廣州清華科技園創(chuàng)新基地番禺石樓鎮(zhèn)創(chuàng)啟路63號(hào)二期2幢101-103室

Diagnostic test
White blood cell count and classification; repeated fungal smear and culture. Bronchial brush or bronchoalveolar lavage can increase the positive rate. Blood sever is rarely positive. Urine, stools, ascites, cerebrospinal fluid, etc. were partially positive for Aspergillus. Suspected pulmonary aspergillosis for antigen antibody X-ray examination.
Treatment program editor
1. Strict control of glucocorticoid and broad-spectrum antibiotics.
2. Active treatment of the primary disease, strengthen supportive therapy, improve the body immunity.
Pathogen treatment
(1) Cryptococcal meningitis patients: ① amphotericin B plus 5-fluorocytosine combination therapy has a synergistic effect. Amphotericin B lmg / (kg · d) intravenous infusion of 5-fluorocytosine 50 ~ 150mg / (kg · d) were administered orally or intravenously 3 times for 6 weeks. Before treatment, treatment every 2 weeks review of BUN and blood to determine the appropriate time interval of medication. Pretreatment renal function test and blood, renal damage and bone marrow suppression should be used with caution (amphotericin B first intravenous infusion of 0.1mg / (kZ · d), after a daily increase of 0.05 ~ 0.10mg / kg up to 1.0 mg / kg, but the daily dose does not exceed 50mg / d, the drug dissolved in 5% glucose solution, the optimal concentration of 0.1mg / ml). Amphotericin B can also be used in combination with rifampicin, but also synergistic effect. ② miconazole (diclofenac) is commonly used in patients with deep fungi that can not tolerate amphotericin B or respond well to poor reactions. Candida, Aspergillus, Cryptococcus, Histoplasma or Cyclospora and other systemic infections effective. Dosage: 0.6g ~ 1.2g / d intravenous infusion of 3 times, intrathecal injection of adult 20mg once every 3 ~ 7d. ③ fluconazole broad-spectrum antifungal effect, good oral absorption, through the blood-brain barrier, 200mg daily 1 or 2 times. (4) Erythromycin orally 400 ~ 2000U / (kg · d), intravenous drip 40 ~ 100U / (kg · d) began; gradually increased to 600 ~ 800U / (kg · d), the total adult does not exceed 3 million ~ 400 million U. [3]
(2) patients with pulmonary cryptococcosis light anti-fungal drugs may not, such as unconditional follow-up may be taken ketoconazole 200mg ~ 400mg / d.
4, nursing
(1) According to the general nursing care routine care. High fever by high heat care routine care.
(2) promptly leave phlegm, blood, urine, stool, cerebrospinal fluid, pus, etc., for routine examination and training.
(3) 3. Closely observe the condition, with particular attention to cough, hemoptysis, breathing, mind changes, etc., if any changes should be promptly linked with the physician.
(4) timely isolation, air disinfection, oral hygiene, skin care and so on.