詳細介紹
Caldesmon鈣結合蛋白(兔單克隆抗體)
廣州健侖生物科技有限公司
鈣調蛋白是細胞第二信使系統(tǒng)的重要成分,在Ca信號系統(tǒng)傳導中起著關鍵的作用,調控生理代謝及基因表達,控制細胞正常的生長和發(fā)育。鈣調蛋白作為第二信使在植物信號轉導中的作用一直是植物生理、細胞生物學和發(fā)育生物學研究的熱點。Ca/CaM是有機體進化過程中zui保守的信號轉導級聯(lián)反應系統(tǒng),這一信號途徑廣泛存在于真核細胞中,并在各種細胞活動如脅迫反應和細胞增殖中起調節(jié)作用。這種Ca/CaM信號系統(tǒng)存在的普遍性和保守性·對鈣調蛋白的研究可以使我們可以更好地利用其功能為人類服務。
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【產品介紹】
細胞定位:細胞漿
適用組織:石蠟/冰凍
陽性對照:甲狀腺髓樣癌
抗原修復:熱修復(EDTA)
抗體孵育時間:30-60min
產品編號 | 抗體名稱 | 克隆型別 |
OB017 | Beta-Catenin(β-連接素) | 14 |
OB018 | 鼠抗人BOB.1單克隆抗體 | MRQ-35 |
OB019 | BRCA-1(乳腺癌1號基因) | MS110 |
OB020 | C4d(補體4d) | polyclonal |
OB021 | CA IX(碳酸酐酶IX) | MRQ-54 |
OB022 | CA-125(卵巢癌抗原) | OC125 |
OB023 | CA-125(卵巢癌抗原) | M11 |
OB024 | CA15-3糖鏈抗原 | DF3 |
OB025 | CA19-9(消化道癌相關抗原) | 121SLE |
OB026 | Calcitonin(降鈣素) | polyclonal |
OB027 | Caldesmon(鈣結合蛋白) | E89 |
Caldesmon鈣結合蛋白(兔單克隆抗體)
診斷檢查
白細胞計數(shù)及分類;反復做真菌直接涂片和培養(yǎng)。支氣管刷液或支氣管肺泡洗液可提高陽性率。血液分離曲菌很少陽性。尿、便、腹水、腦脊液等分離曲菌部分陽性。疑有肺曲菌病時作抗原抗體X線檢查。
治療方案編輯
1.嚴格掌握糖皮質激素及廣譜抗生素的應用。
2.積極治療原發(fā)病,加強支持療法,提高機體免疫力。
3.病原治療
(1)對隱球菌腦膜炎患者:①用二性霉素B加5-氟胞嘧啶聯(lián)合治療具有協(xié)同作用。二性霉素B lmg/(kg·d)靜滴、5-氟胞嘧啶50~150mg/(kg·d)分3次口服或靜滴共6周。治療前、治療中每2周復查BUN及血象以確定用藥的適當時間間隔。治療前測腎功及血象,對腎功損害及骨髓抑制的患者應慎用(二性霉素B*靜脈滴注劑量為0.1mg/(kZ·d),以后每日增加0.05~0.10mg/kg直至1.0mg/kg,但每日劑量不超過50mg/d,藥物溶解于5%葡萄糖液,*濃度為0.1mg/m1)。二性霉素B也可與利福平聯(lián)合應用,亦有協(xié)同作用。②咪康唑(雙氯苯咪唑)常用于不能耐受二性霉素B或治療反應不佳的深部真菌患者。對念珠菌、曲菌、隱球菌、組織胞漿菌或環(huán)孢子菌等全身感染有效。劑量:0.6g~1.2g/d分3次靜滴,鞘內注射成人20mg每3~7d一次。③氟康唑有廣譜抗真菌作用,口服吸收良好,能透過血腦屏障,200mg每日1~2次。④球紅霉素口服400~2000U/(kg·d),靜滴40~100U/(kg·d)開始;漸增至600~800U/(kg·d),成人總量不超過300萬~400萬U。[3]
(2)肺部隱球菌病輕型患者可不用抗真菌藥物,如無條件隨訪可口服酮康唑200mg~400mg/d。
4、護理
(1)按傳染病一般護理常規(guī)護理。高熱時按高熱護理常規(guī)護理。
(2)及時留送痰、血、尿、糞便、腦脊髓液、膿液等,進行常規(guī)檢查及培養(yǎng)。
(3)3.密切觀察病情,特別注意咳嗽、咯血、呼吸、神志改變等,如有變化應及時與醫(yī)師。
(4)及時做好隔離、空氣消毒、口腔衛(wèi)生、皮膚護理等。
我司還提供其它進口或國產試劑盒:登革熱、瘧疾、流感、A鏈球菌、合胞病毒、腮病毒、乙腦、寨卡、黃熱病、基孔肯雅熱、克錐蟲病、違禁品濫用、肺炎球菌、軍團菌、化妝品檢測、食品安全檢測等試劑盒以及日本生研細菌分型診斷血清、德國SiFin診斷血清、丹麥SSI診斷血清等產品。
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【公司名稱】 廣州健侖生物科技有限公司
【市場部】 楊永漢
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【騰訊 】
【公司地址】 廣州清華科技園創(chuàng)新基地番禺石樓鎮(zhèn)創(chuàng)啟路63號二期2幢101-103室
Diagnostic test
White blood cell count and classification; repeated fungal smear and culture. Bronchial brush or bronchoalveolar lavage can increase the positive rate. Blood sever is rarely positive. Urine, stools, ascites, cerebrospinal fluid, etc. were partially positive for Aspergillus. Suspected pulmonary aspergillosis for antigen antibody X-ray examination.
Treatment program editor
1. Strict control of glucocorticoid and broad-spectrum antibiotics.
2. Active treatment of the primary disease, strengthen supportive therapy, improve the body immunity.
Pathogen treatment
(1) Cryptococcal meningitis patients: ① amphotericin B plus 5-fluorocytosine combination therapy has a synergistic effect. Amphotericin B lmg / (kg · d) intravenous infusion of 5-fluorocytosine 50 ~ 150mg / (kg · d) were administered orally or intravenously 3 times for 6 weeks. Before treatment, treatment every 2 weeks review of BUN and blood to determine the appropriate time interval of medication. Pretreatment renal function test and blood, renal damage and bone marrow suppression should be used with caution (amphotericin B first intravenous infusion of 0.1mg / (kZ · d), after a daily increase of 0.05 ~ 0.10mg / kg up to 1.0 mg / kg, but the daily dose does not exceed 50mg / d, the drug dissolved in 5% glucose solution, the optimal concentration of 0.1mg / ml). Amphotericin B can also be used in combination with rifampicin, but also synergistic effect. ② miconazole (diclofenac) is commonly used in patients with deep fungi that can not tolerate amphotericin B or respond well to poor reactions. Candida, Aspergillus, Cryptococcus, Histoplasma or Cyclospora and other systemic infections effective. Dosage: 0.6g ~ 1.2g / d intravenous infusion of 3 times, intrathecal injection of adult 20mg once every 3 ~ 7d. ③ fluconazole broad-spectrum antifungal effect, good oral absorption, through the blood-brain barrier, 200mg daily 1 or 2 times. (4) Erythromycin orally 400 ~ 2000U / (kg · d), intravenous drip 40 ~ 100U / (kg · d) began; gradually increased to 600 ~ 800U / (kg · d), the total adult does not exceed 3 million ~ 400 million U. [3]
(2) patients with pulmonary cryptococcosis light anti-fungal drugs may not, such as unconditional follow-up may be taken ketoconazole 200mg ~ 400mg / d.
4, nursing
(1) According to the general nursing care routine care. High fever by high heat care routine care.
(2) promptly leave phlegm, blood, urine, stool, cerebrospinal fluid, pus, etc., for routine examination and training.
(3) 3. Closely observe the condition, with particular attention to cough, hemoptysis, breathing, mind changes, etc., if any changes should be promptly linked with the physician.
(4) timely isolation, air disinfection, oral hygiene, skin care and so on.