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TPH-1 (D10C10) Rabbit mAb #12339 Cell Signaling
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上??泼羯镤N售TPH-1 (D10C10) Rabbit mAb #12339 Cell Signaling,CST原裝品質(zhì),*,訂購TPH-1 (D10C10) Rabbit mAb #12339 Cell Signaling,詳情請(qǐng)咨詢銷售人員!
產(chǎn)品詳細(xì)參數(shù)如下>>>>
產(chǎn)品名稱:TPH-1 (D10C10) Rabbit mAb #12339 Cell Signaling
貨號(hào):12339
品牌:CST(cell signaling)
抗體來源:Rabbit
克隆類型:Monoclonal
規(guī)格:
No. | Size | Price |
12339S | 100 ul (10 western blots) | 詢價(jià) |
抗體應(yīng)用:
Applications | Reactivity | Sensitivity | MW (kDa) | Isotype |
W IP | M (H) | Endogenous | 51 | Rabbit IgG |
Applications Key: W=Western Blotting IP=Immunoprecipitation
Reactivity Key: H=Human M=Mouse
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on * sequence homology.
特異性/敏感度:TPH-1 (D10C10) Rabbit mAb recognizes endogenous levels of total TPH-1 protein.
來源及純化方法:Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human TPH-1 protein.
抗體背景:
Tryptophan hydroxylase (TPH) is the rate-limiting enzyme in the biosynthesis of serotonin (1) by converting tryptophan to 5-hydroxy-L-tryptophan (2). Two isoforms of TPH exist: TPH-1 is mainly expressed in the periphery, whereas the expression of TPH-2 is restricted to neuronal cells and the central nervous system (3). Most of the serotonin found throughout the body is synthesized by TPH-1 in enterochromaffin cells of the gastrointestinal tract. Targeted disruption of the tph1 gene results in low levels of circulating and tissue serotonin (4).
關(guān)鍵詞:CST,抗體,一抗{byao_back}{byao_back2}
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