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BPS Bioscience Inc.
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當(dāng)前位置:BPS Bioscience Inc.>>Ubiquitination>> 27706-1LDN-57444

LDN-57444

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產(chǎn)品型號(hào)27706-1

品       牌BPS Bioscience

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更新時(shí)間:2023-12-19 22:37:26瀏覽次數(shù):158次

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●Purchase●DescriptionLDN-57444isacellpermeableubiquitinC-terminalhydrolase(UCH-L1)inhibitor(Ki=0
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Description

LDN-57444 is a cell permeable ubiquitin C-terminal hydrolase (UCH-L1) inhibitor (Ki=0.4 μM). Decreases proteasome activity and increases levels of ubiquitinated proteins. Induces apoptosis and causes dramatic alterations in synaptic protein distribution and spine morphology in vivo. LDN-57444 is a useful tool to study UCH-L1 in different pathological conditions such as cancer and neurodegeneration.

Synonyms
1H–Indole–2,3–dione, 5–chloro–1–[(2,5–dichlorophenyl)methyl]–, 3–(O–acetyloxime)

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