The Angiotensin converting enzyme 2 (ACE2) Inhibitor Screening Assay Kit is a 96-well homogeneous fluorogenic assay designed to measure the exopeptidase activity of ACE2 for screening and profiling applications. The ACE2 kit contains enough purified ACE2 amino acids 18-740 (BPS Bioscience #11003), ACE2 substrate, and ACE2 buffer for 100 reactions.

Figure 1: Illustration of the assay principle. Cleavage of the peptide by ACE2 releases L-phenylalanine, which is measured by a two-step reaction and detection of a fluorogenic product. The fluorescence signal increases in proportion to ACE2 activity.

Note: For an assay with higher sensitivity, please refer to Fluoro-Verse™ ACE2 Inhibitor Assay Kit (BPS Bioscience #78847).

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