NLRP3 Knockdown THP-1 Cell Pool is a cell pool of THP-1 human monocytic cells. This cell pool was generated by using NLRP3 Human shRNA Lentivirus (BPS Bioscience #82122) to create a THP-1 cell pool with stable knockdown of NLRP3 (NLR family pyrin domain containing 3). THP-1 cells are the most commonly used model cell line in the study of inflammasome activation as they express high levels of NLRP3 and pro-caspase-1.

Purchase of this cell line is for research purposes only; commercial use requires a separate license. View the full terms and conditions.