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當(dāng)前位置:BPS Bioscience Inc.>>Antibodies>> 100761Anti-BCMA-Anti-CD19-Anti-CD3 Trispecific Molecule
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產(chǎn)品型號(hào)100761
品 牌BPS Bioscience
廠商性質(zhì)生產(chǎn)商
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更新時(shí)間:2023-11-10 20:35:29瀏覽次數(shù):218次
聯(lián)系我時(shí),請(qǐng)告知來自 化工儀器網(wǎng)AAV-6 Anti-CD19 CAR (CD19 ScFv-CD8-
Anti–5–mC monoclonal antibody 33D3
The Anti-BCMA-Anti-CD19-Anti-CD3 Trispecific Molecule is engineered to bind to three different targets simultaneously: 1) BCMA, a B cell antigen that is highly expressed by mature B cells and malignant myeloma cells, 2) CD19, a B-cell marker that is a target for many leukemias and lymphomas, and 3) CD3, a T cell receptor activation signal that leads to cytokine secretion. The multi-functionality of this trispecific molecule allows it to bind to BCMA and CD19 on the tumor cell and CD3 on T cells simultaneously, thus bringing T lymphocytes closer to the cancer cells. The binding event targets the tumor while providing co-stimulatory signals that promote T cell expansion and cytotoxicity against BCMA+ and CD19+ cancer cells.
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