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BPS Bioscience Inc.
中級(jí)會(huì)員 | 第3年

當(dāng)前位置:BPS Bioscience Inc.>>細(xì)胞庫(kù) / 細(xì)胞培養(yǎng)>> Adenosine A2A Receptor Functional HEK293 Cell Line

Adenosine A2A Receptor Functional HEK293 Cell Line

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更新時(shí)間:2023-10-12 10:01:38瀏覽次數(shù):117次

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  • 數(shù)量:

    1

  • 供應(yīng)商:

    BPS Bioscience

  • 細(xì)胞類型:

    穩(wěn)轉(zhuǎn)細(xì)胞系

  • 品系:

    HEK293

  • 組織來(lái)源:

    /

  • 相關(guān)疾?。?/span>

    多種

  • 物種來(lái)源:

    human

  • 免疫類型:

    多種

  • 器官來(lái)源:

    無(wú)

  • 運(yùn)輸方式:

    干冰

  • 年限:

    10

  • 生長(zhǎng)狀態(tài):

    良好

  • CAS號(hào):

    無(wú)

  • 英文名:

    Adenosine A2A Receptor Functional HEK293 Cell Line

  • 注冊(cè)證號(hào):

    /

  • 規(guī)格:

    2管

Adenosine A2a receptor (A2aR or ADORA2A) stably expressed in HEK-293 cells. A2aR is a member of the seven transmembrane G protein-coupled receptor (GPCR) family. The activity of A2aR is mediated by G?s protein which activates adenylyl cyclase, resulting in the synthesis of intracellular cAMP. The level of cAMP correlates with the respective adenosine (agonist) level, and the cell line can be used to measure the EC50 and IC50 values of A2aR agonists or antagonists in a quantitative manner. Binding of extracellular adenosine ligand or its stable analog NECA (5′-(N-Ethylcarboxamido) adenosine) to the A2aR expressed on the surface of this cell line induces cAMP expression.

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