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BPS Bioscience Inc.
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當(dāng)前位置:BPS Bioscience Inc.>>細(xì)胞庫 / 細(xì)胞培養(yǎng)>> GR-GAL4 Luciferase Reporter Jurkat Cell Line

GR-GAL4 Luciferase Reporter Jurkat Cell Line

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品       牌BPS Bioscience

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更新時(shí)間:2024-11-24 18:32:54瀏覽次數(shù):142次

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數(shù)量:1供應(yīng)商:BPSBioscience細(xì)胞類型:穩(wěn)轉(zhuǎn)細(xì)胞系品系:Jurkat(cloneE6-1)
  • 數(shù)量:

    1

  • 供應(yīng)商:

    BPS Bioscience

  • 細(xì)胞類型:

    穩(wěn)轉(zhuǎn)細(xì)胞系

  • 品系:

    Jurkat (clone E6-1), human T lymphoblast, suspension

  • 組織來源:

    /

  • 相關(guān)疾?。?/span>

    多種

  • 物種來源:

    human

  • 免疫類型:

    多種

  • 器官來源:

  • 運(yùn)輸方式:

    干冰

  • 年限:

    10

  • 生長狀態(tài):

    良好

  • CAS號(hào):

  • 英文名:

    GR-GAL4 Luciferase Reporter Jurkat Cell Line

  • 注冊(cè)證號(hào):

    /

  • 規(guī)格:

    2管

The Glucocorticoid Receptor (GR)-GAL4 Luciferase Reporter Jurkat Cell Line contains an engineered transcription factor stably integrated into the genome of Jurkat cells, which consists of the glucocorticoid receptor ligand binding domain fused to the DNA binding domain of GAL4. This fusion construct activates firefly luciferase expression which is under the control of a multimerized GAL4 upstream activation sequence (UAS). This allows for specific detection of glucocorticoid-induced activation of the glucocorticoid receptor without the need for individual transcriptional targets and with low cross-reactivity for other nuclear receptor pathways. This cell line is validated for response to stimulation of dexamethasone and to the treatment with mifepristone, an inhibitor of the glucocorticoid signaling pathway.

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