ABL1抗體

抗原
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
別名 ABL1, ABL, CABL, ABLL, cb272, JTK7, bcr/abl, c-ABL, p150, v-abl, AI325092, Abl, E430008G22Rik, c-Abl, MTP
抗原表位
其他選擇 AA 613-641, Center
pTyr412(52),pTyr204 (37),pTyr245 (32),pThr735 (26),C-Term (17),pTyr134 (17),pThr754 (14),pTyr272 (14),pTyr276 (13),pTyr283 (13),pTyr89 (13),Internal Region (12),pSer569 (12),pThr413 (12),pTyr115 (12),pTyr185 (12),pTyr253 (12),pTyr70 (12),Tyr412 (11),pTyr393 (11),N-Term (10),AA 577-650 (7),AA 612-642 (7),Tyr204 (6),Tyr245 (6),Center (3),SH2 Domain (3),Ser588 (3),Tyr134 (3),AA 231-260 (2),AA 741-769 (2),AA 851-881 (2),Ala198 (2),Ser121 (2),Thr735 (2),Tyr393 (2),Tyr429 (2),pThr734 (2),pThr753 (2),pTyr439 (2),AA 156-205 (1),AA 188-238 (1),AA 196-245 (1),AA 361-410 (1),AA 391-395 (1),AA 406-455 (1),AA 550-600 (1),AA 613-641 (1),AA 68-117 (1),AA 701-750 (1),AA 834-883 (1),AA 850-900 (1),AA 861-910 (1),AA 905-1089 (1),AA 929-1020 (1),Glu883 (1),Gly418 (1),Leu406 (1),Middle Region (1),Ser12 (1),Ser120 (1),Ser210 (1),Tyr251 (1),pThr134 (1),pThr245 (1),pTyr251 (1)
適用
其他選擇 Murine
Human(516),Murine (334),Rat ((Rattus)) (276),Pig (Porcine) (180),Bovine (169),Dog (Canine) (156),Chicken (60),Guinea Pig (48),Monkey (4),Bird (Avian) (1),Rabbit (1)
宿主
其他選擇 Rabbit
Rabbit(509),Mouse (21)
克隆類型 (克隆位點)
多克隆 (RB34442)
標記
其他選擇 非結合性
Biotin(25),FITC (22),HRP (22),Alexa Fluor 350 (17),Alexa Fluor 488 (17),Alexa Fluor 555 (17),Alexa Fluor 647 (17),Cy3 (17),Cy5 (17),Cy5.5 (17),Cy7 (17),APC (8),Alkaline Phosphatase (AP) (8),PE (8)
應用范圍
其他選擇 Western Blotting (WB), Immunohistochemistry (IHC)
Western Blotting (WB)(310),ELISA (172),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (170),Immunohistochemistry (IHC) (137),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (108),Immunofluorescence (IF) (50),Dot Blot (DB) (26),Immunoprecipitation (IP) (20),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (15),Immunocytochemistry (ICC) (12),Flow Cytometry (FACS) (11),Enzyme Immunoassay (EIA) (7),Immunohistochemistry (Frozen Sections) (IHC (fro)) (3),Proximity Ligation Assay (PLA) (2)
[Pubmed] 2 references available
規(guī)格 400 μL
發(fā)貨至 中國 (更改)
發(fā)貨時間 9至13個工作日

ABL1抗體

產品細節(jié)

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產品細節(jié)

顯示 隱藏
免疫原 This Mouse Abl1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 613-641 AA from the Central region of mouse Abl1.
克隆位點 RB34442
亞型 Ig
特異性 This Mouse Abl1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 612-642 amino acids from the Central region of human Mouse Abl1.
純化方法 This antibody is purified through a protein A column, followed by peptide affinity purification.

目標詳細情況

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目標詳細情況

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別名 Abl1
背景 Protein kinase that regulates key processes linked to cell growth and survival. Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.
Synonyms: Tyrosine-protein kinase ABL1,Abl1,Abl
分子量 122673 DA
基因ID 11350
NCBI Accession NP_001106174, NP_033724
UniProt P00520
研究領域 Phospho-specific antibodies, Cell Signaling, Cell Structure, Protein Modifications, Cancer, Chromatin, Signaling

使用細節(jié)

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應用備注 WB = 1:1000, IHC = 1:10-50
限制 For Research Use only

貯存及處理

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貯存及處理

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狀態(tài) Liquid
濃度 0.43 mg/mL
緩沖液 PBS with 0.09 % (W/V) sodium azide
儲存液 Sodium azide
注意事項 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
儲存條件 4 °C/-20 °C
儲存方法 Mouse Abl1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
有效期 6 months

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