XBP1 抗體

抗原
X-Box Binding Protein 1 (XBP1)
別名 treb5, xXBP1, xbp2, XBP1P1, XBPP1, xbp1, TREB5, XBP-1, XBP2, D11Ertd39e, TREB-5, HTF, cb918, id:ibd1195, trebf, wu:fb02h05, wu:fb63f10, xbp1a, xbp1b
抗原表位
其他選擇 AA 62-91, Center
C-Term(25),N-Term (17),AA 123-225 (12),Internal Region (12),AA 224-252 (7),AA 2-160 (5),AA 70-100 (5),AA 1-261 (3),AA 1-74 (2),AA 217-244 (2),AA 130-261 (1),AA 188-287 (1),AA 35-249 (1),AA 62-91 (1),AA 90-261 (1)
適用
其他選擇 Human
Human(124),Murine (59),Rat ((Rattus)) (41),Bovine (15),Pig (Porcine) (15),Chicken (13),Dog (Canine) (4),Xenopus laevis (1),Zebrafish (Danio rerio) (1)
宿主
其他選擇 Rabbit
Rabbit(72),Mouse (47),Goat (8),Chicken (5)
克隆類型 (克隆位點)
多克隆 (RB21824)
標記
其他選擇 非結(jié)合性
FITC(4),HRP (4),APC (3),Alkaline Phosphatase (AP) (3),PE (3),Biotin (2),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1)
應(yīng)用范圍
其他選擇 Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
Western Blotting (WB)(119),ELISA (67),Immunocytochemistry (ICC) (29),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (22),Immunohistochemistry (IHC) (15),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Immunofluorescence (IF) (9),Flow Cytometry (FACS) (8),Enzyme Immunoassay (EIA) (7),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (6),Immunoassay (IA) (3),Dot Blot (DB) (2),Immunoprecipitation (IP) (2),Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
[Pubmed] 1 reference available
規(guī)格 400 μL
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XBP1 抗體

產(chǎn)品細節(jié)

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產(chǎn)品細節(jié)

顯示 隱藏
免疫原 This XBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-91 AA from the Central region of human XBP1.
克隆位點 RB21824
亞型 Ig
特異性 This XBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-100 amino acids from the Central region of human XBP1.
預(yù)測反應(yīng) Cow (Bovine),Mouse (Murine),Rat (Rattus)
純化方法 This antibody is purified through a protein A column, followed by peptide affinity purification.

目標詳細情況

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目標詳細情況

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別名 XBP1
背景 XBP1 encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1). The resulting loss of 26 nt from the spliced mRNA causes a frame-shift and an isoform XBP1(S), which is the functionally active transcription factor.
Synonyms: Tax-responsive element-binding protein 5, X-box-binding protein 1, XBP-1,XBP2, TREB5, XBP1
分子量 28695 DA
基因ID 7494
UniProt P17861
研究領(lǐng)域 Transcription Factors

使用細節(jié)

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使用細節(jié)

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應(yīng)用備注 WB = 1:1000, IHC = 1:50-100, FACS = 1:10-50
限制 For Research Use only

貯存及處理

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貯存及處理

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狀態(tài) Liquid
濃度 0.48 mg/mL
緩沖液 PBS with 0.09 % (W/V) sodium azide
儲存液 Sodium azide
注意事項 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
儲存條件 4 °C/-20 °C
儲存方法 Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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