AAK1 (N-Term) 抗體

抗原
AAK1
別名 5530400K14Rik, 9630042K20, AU067724, AU067726, BC028270, C79663, D6Ertd245e, R75501, mKIAA1048, RGD1563580
抗原表位
其他選擇 N-Term
C-Term(19),Internal Region (12),N-Term (11),AA 278-306 (7),AA 1-474 (1),AA 194-223 (1),AA 271-320 (1),AA 310-360 (1),AA 315-415 (1),AA 350-410 (1),AA 63-304 (1),AA 704-822 (1),Center (1)
適用
其他選擇 Human, Murine, Rat ((Rattus))
Human(79),Murine (59),Rat ((Rattus)) (48),Bovine (2),Dog (Canine) (1),Horse (Equine) (1),Monkey (1),Pig (Porcine) (1),Rabbit (1)
宿主
其他選擇 Rabbit
Rabbit(80),Goat (5),Mouse (3)
克隆類型
多克隆
標(biāo)記
其他選擇 非結(jié)合性
Biotin(2),FITC (2),HRP (2),APC (1),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Alkaline Phosphatase (AP) (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1),PE (1)
應(yīng)用范圍
其他選擇 ELISA, Western Blotting (WB), Immunocytochemistry (ICC)
Western Blotting (WB)(79),ELISA (36),Immunohistochemistry (IHC) (12),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (10),Immunocytochemistry (ICC) (8),Enzyme Immunoassay (EIA) (5),Immunofluorescence (IF) (3),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (2),Immunoprecipitation (IP) (2),Immunoassay (IA) (1)
規(guī)格 0.1 mg
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發(fā)貨時(shí)間 24至29個(gè)工作日

AAK1 (N-Term) 抗體

產(chǎn)品細(xì)節(jié)

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產(chǎn)品細(xì)節(jié)

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免疫原 The immunogen for anti-Aak1 antibody: antibody was raised against a 20 amino acid peptide near the amino terminus of the human Aak1.
預(yù)測反應(yīng) Human Mouse Rat
產(chǎn)品特性 Ap2-Associated Protein Kinase 1 (Aak1) Is A Member Of The Ark1/Prk1 Subfamily Of Ser/Thr Protein Kinases That Are Thought To Regulate Endocytosis By Phosphorylating The Accessory Endocytic Components. Aak1 Interacts With And Phosphorylates The Mu2 Subunit Of The Ap-2 Complex, Which Promotes Binding Of The Ap-2 To Tyrosine Based (Yxxphi) Internalization Motif-Containing Receptors And Subsequent Receptor Endocytosis. At Least Two Isoforms Of Aak1 Are Known To Exist, The Longer Isoform Contains An Extended Carboxy-Terminus That Contains An Additional Clathrin-Binding Domain. Overexpression Of This Long Isoform Or Aak1 Depletion By Rna Interference Impairs Transferrin Recycling From The Early/Sorting Endosome, Suggesting That Aak1 Functions At Multiple Steps Of The Endosomal Pathway By Regulating Transferrin Internalization And Its Recycling Back To The Plasma Membrane.
純化方法 Affinity chromatography purified via peptide column

AAK1 (N-Term) 抗體目標(biāo)詳細(xì)情況

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目標(biāo)詳細(xì)情況

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背景 (NT) Ap2-Associated Protein Kinase 1

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AAK1 (N-Term) 抗體使用細(xì)節(jié)

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應(yīng)用備注 Aak1 antibody can be used for detection of Aak1 by Western blot at 1 - 2?μg/mL
限制 For Research Use only

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注意事項(xiàng) As with all antibodies care should be taken to avoid repeated freeze thaw cycles.
Antibodies should not be exposed to prolonged high temperatures.
儲(chǔ)存條件 4 °C
儲(chǔ)存方法 Aak1 antibody can be stored at 4 °C,

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