英文名稱 BMP8
中文名稱 骨形態(tài)發(fā)生蛋白8抗體
別    名 one morphogenetic protein 8; BMP-8; BMP 8; BMP8; OP2; Osteogenic protein 2; BMP-8B; Bmp8b; BMP8B_HUMAN; BMP-8A; Bmp8b; BMP8B_HUMAN; Bone morphogenetic protein 8B; BMP8B bone morphogenetic protein 8b; BMP8A bone morphogenetic protein 8a; FLJ14351; FLJ45264; OP 2; Osteogenic protein-2; bone morphogenetic protein 8B preproprotein.
骨形態(tài)發(fā)生蛋白8抗體  
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 細胞生物  免疫學(xué)  生長因子和激素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 45kDa
細胞定位 分泌型蛋白 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human BMP8
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has led to speculation of possible bone inductive activity. [provided by RefSeq, Jul 2008].

Function:
Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.

Subunit:
Homodimer; disulfide-linked.

Subcellular Location:
Secreted.

Similarity:
Belongs to the TGF-beta family.

Database links:

Entrez Gene: 656 Human

Entrez Gene: 12164 Mouse

Omim: 602284 Human

SwissProt: P34820 Human

SwissProt: P55105 Mouse

Unigene: 664022 Human

Unigene: 439764 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.xy-9740R CNTD2細胞周期蛋白N端結(jié)構(gòu)域蛋白2抗體
xy-8550R Coronin 1a肌動蛋白結(jié)合蛋白CORO1A抗體
xy-2080R Cecropin抗菌肽/天蠶素抗體
xy-1809R Camk1g鈣/鈣調(diào)蛋白依賴蛋白激酶IG抗體
xy-1679R CCR8細胞表面趨化因子受體8抗體
xy-0262R CMTM2趨化素樣因子超家族成員2抗體
xy-9515R CTH胱硫醚γ裂解酶抗體
xy-1277R CFTR囊性纖維化跨膜轉(zhuǎn)運調(diào)節(jié)因子抗體
xy-1330R CKIP-1酪蛋白激酶2相互作用蛋白1抗體
xy-1286R CD40LCD40L抗體
xy-10033R Alpha s1 Caseinα-s1酪蛋白抗體
xy-0716R CIDEBCIDEB抗體
xy-1186R Scavenging Receptor SR-BI高密度脂蛋白受體/清道夫受體抗體
xy-9124R COPS7A信號轉(zhuǎn)導(dǎo)蛋白亞基7A抗體
xy-0615R Survivin細胞凋亡抑制因子抗體
xy-0936R Clostridium perfringens type DD型產(chǎn)氣莢膜梭菌抗體
xy-0063R Calcitonin降鈣素抗體
xy-15094R C20orf1420號染色體開放閱讀框14抗體
xy-0743R CTGF結(jié)締組織生長因子抗體