英文名稱 ARVCF
中文名稱 精神分裂癥與犰狳重復(fù)基因抗體
別    名 Armadillo repeat gene deletes in velocardiofacial syndrome; Armadillo repeat protein; Armadillo repeat protein deleted in velo cardio facial syndrome; Armadillo repeat protein deleted in velo-cardio-facial syndrome; ARVC_HUMAN; Arvcf; FLJ35345; OTTHUMP00000028704; OTTHUMP00000198346; OTTHUMP00000198347; OTTHUMP00000198348.
精神分裂癥與犰狳重復(fù)基因抗體
說 明 書 0.2ml  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 105kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ARVCF
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Armadillo Repeat gene deleted in Velo-Cardio-Facial syndrome (ARVCF) is a member of the catenin family. This family plays an important role in the formation of adherens junction complexes, which are thought to facilitate communication between the inside and outside environments of a cell. The ARVCF gene was isolated in the search for the genetic defect responsible for the autosomal dominant Velo-Cardio-Facial syndrome (VCFS), a relatively common human disorder with phenotypic features including cleft palate, conotruncal heart defects and facial dysmorphology. The ARVCF gene encodes a protein containing two motifs, a coiled coil domain in the N-terminus and a 10 armadillo repeat sequence in the midregion. Since these sequences can facilitate protein-protein interactions ARVCF is thought to function in a protein complex. In addition, ARVCF contains a predicted nuclear-targeting sequence suggesting that it may have a function as a nuclear protein. [provided by RefSeq, Jun 2010].

Function:
Involved in protein-protein interactions at adherens junctions.

Subunit:
Interacts (via the extreme C-terminus) with FRMPD2 (via the PDZ 2 domain).

Tissue Specificity:
Found in all the examined tissues including heart, brain, liver and kidney. Found at low level in lung.

Similarity:
Belongs to the beta-catenin family.
Contains 10 ARM repeats.

Gene ID:
421

Database links:

Entrez Gene: 421 Human

Omim: 602269 Human

SwissProt: O00192 Human

Unigene: 699354 Human

Unigene: 713616 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.xy-3532R PLCG 2磷酯酶Cγ2抗體
xy-3318R Phospho-PDGFRA(Tyr1018)磷酸化血小板源性生長因子受體-α抗體
xy-3319R Phospho-PDGFRA(Tyr754)磷酸化血小板源性生長因子受體-α抗體
xy-1346R P73 proteinP73腫瘤抑制基因抗體
xy-4958R PCGF1表觀抑制因子Polycomb家族成員PCGFl蛋白抗體
xy-12070R P2Y10G蛋白偶聯(lián)嘌呤受體p2y10抗體
xy-0190R PACAP-27/38腺苷酸環(huán)化酶激活肽-27/38抗體
xy-0534R p19ARFp19ARF抑癌基因抗體
xy-0741R CDKN1Ap21蛋白抗體
xy-1204R P2Y1P2Y1受體抗體/嘌呤受體抗體
xy-0427R P311 protein神經(jīng)再生相關(guān)蛋白抗體
xy-0637R P38 MAPK絲裂原活化蛋白激酶p38α抗體
xy-1069R proCNP促尿鈉排泄肽前體C抗體
xy-0739R PAP2c磷脂酸磷酸酶2C抗體
xy-1199R PAX1配對(duì)盒基因1抗體
xy-1187R PAX2配對(duì)盒基因2抗體
xy-3520R PAK2p21激活激酶2抗體
xy-3534R PLC beta 3磷酯酶Cβ3抗體
xy-3328R Phospho-PEA15 (Ser104)磷酸化星形膠質(zhì)細(xì)胞PEA15抗體
xy-3329R Phospho-PEA15(Ser116)磷酸化星形膠質(zhì)細(xì)胞PEA15抗體
xy-1712R Pan Cytokeratin廣譜細(xì)胞角蛋白PCK抗體