microFIND®, designed to perform Fluorescence in Situ Hybridization （FISH） on biological samples, consists of a functionalized （coated） glass slide and 1 to 4 microfluidic channels （pads） to be used as

microFIND®, designed to perform Fluorescence in Situ Hybridization (FISH) on biological samples, consists of a functionalized (coated) glass slide and 1 to 4 microfluidic channels (pads) to be used as effective alternative to standard slides, for sample processing.

microFIND® offers your desired level of automation from semi to fully- automated solutions for FISH assays. Two different models are currently available: autoFIND S andautoFIND F.

• Enables a straightforward route to FISH test automation

• Enhances assay reproducibility and standardization of FISH protocols

• Automates the sample preparation step

• Allows more efficient and faster image acquisition

Proprietary coating

microFIND® is a slide with a proprietary coating, coupled with microfluidic compartments or microchannels, where cells are loaded and processed for FISH: after hybridizations slides are further analyzed by fluorescence microscopy using conventional manual or automated systems.

• Optimum nuclei and metaphase spreading in controlled environment (temperature and humidity)

• Cell amount
  Cells are always consistently in a statistically representative number for diagnostic use for onco-haematological diseases (cell from Bone Marrow and Peripheral Blood average 3.000 up to 5.000 cells/microFIND, cells from voided urine specimen average 800 cells up to 1.5000 cells/microFIND)

• No cross contamination
  Cells and probes are physically separated on microFIND with no possibility of cross contamination

• You can expand your abilities without ever compromising the quality of results

• Variability and human error are reduced with increased automation, building confidence in the results and a great level of standardization inter and intra laboratory operations

Suitable samples

microFIND®, used as alternative to standard slides, is designed to replace standard FISH sample preparation on slides, to fully automated FISH for the following biological samples:

• Fixed cells in the form of standard cytogenetic pellet from peripheral blood PB and bone marrow BM, either primary or cultured

• Fixed cells in the form of cytogenetic pellet from spontaneous urine

• Living white blood cells, not previously fixed, from PB and BM, either primary or cultured, or pre-selected by IMAC (Immobilized Metal Ion Affinity Chromatography) or FACS (Fluorescent-Activated Cell Sorting) methods

Nanotech coating and cell adhesion in microfluidic enviroment

microFIND 90%

Poly D Lys 30%

Glass 13%

microFIND® for autoFIND

• microFIND® for autoFIND S
• microFIND® for autoFIND F

microFIND® 1L is a consumable device to use combined with autoFIND S.
microFIND® is constituted by a coated glass slide and a microfluidic element (microchannel).